Thalassemia and pregnancy complications

Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin protein red cells that carries oxygen. The results large numbers being destroyed, leads to anemia. This alpha- beta-chain ratio causes unpaired chains precipitate and destruction cell precursors bone marrow (ineffective erythropoiesis) circulation (hemolysis). Affected individuals with thalassemia have variable degrees anemia extramedullary hematopoiesis, turn can cause changes, impaired growth, iron overload. Recurrent pregnancy loss (RPL), also known as recurrent miscarriages, defined by consecutive two more pregnancies same partner having no than one living child. Objective current review was determine maternal fetal outcomes women complicated .Conclusion: There are many changes complications stress make symptoms worse . should be considered high risk always preceded complete preconception assessment.